OC-0038: Patterns in ano-rectal dose maps and the risk of late toxicity after prostate radiotherapy
نویسندگان
چکیده
منابع مشابه
The effect of Rectal Retractor, a rectal protector on rectal dose in radical prostate radiotherapy
Introduction: The close proximity of the rectum tissue to the prostate gland results in rectal toxicity during prostate radiotherapy. Rectal Retractor (RR) is a rectal displacement technique that inserts into the rectum, as a result, the lateral and dorsal part of the rectal wall push away from high dose areas. The aim of this study was to investigate the dosimetric consequence...
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BACKGROUND AND PURPOSE For the first time, delivered dose to the rectum has been calculated and accumulated throughout the course of prostate radiotherapy using megavoltage computed tomography (MVCT) image guidance scans. Dosimetric parameters were linked with toxicity to test the hypothesis that delivered dose is a stronger predictor of toxicity than planned dose. MATERIAL AND METHODS Dose-s...
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The purpose of this study is to examine risk factors for late rectal toxicity for localized prostate cancer patients treated with helical tomotherapy (HT). The patient cohort of this retrospective study was composed of 241 patients treated with HT and followed up regularly. Toxicity levels were scored according to the Radiation Therapy Oncology Group grading scale. The clinical and dosimetric p...
متن کاملVoxel-based population analysis for correlating local dose and rectal toxicity in prostate cancer radiotherapy.
The majority of current models utilized for predicting toxicity in prostate cancer radiotherapy are based on dose-volume histograms. One of their main drawbacks is the lack of spatial accuracy, since they consider the organs as a whole volume and thus ignore the heterogeneous intra-organ radio-sensitivity. In this paper, we propose a dose-image-based framework to reveal the relationships betwee...
متن کاملComparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy.
PURPOSE To compare the fits of normal-tissue complication probability (NTCP) models based on rectal dose-wall histograms (DWHs) vs. dose-volume histograms (DVHs) when the two are used to analyze a common set of late rectal toxicity data. METHODS AND MATERIALS Data were analyzed from 128 prostate cancer patients treated with 3-dimensional conformal radiotherapy (3D-CRT) at The University of Te...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2017
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(17)30482-6